Microencapsulated Retinol Powder:

Stable Vitamin A Derivative with Targeted Anti-Aging & Cellular Renewal

Basic Information

• INCI: Retinyl Palmitate (Microencapsulated)

• CAS No.: 79-81-2

• Molecular Formula: C₃₆H₆₀O₂

• Purity: ≥95% (HPLC, all-trans isomer)

• Particle Size: 10-50μm (Controlled release)

• Stability:

  • Oxygen stability: 18 months (vs 3 months for pure retinol)

  • pH Range: 5.0-7.0 (Optimal activity)

• Certifications: NSF, ISO 9001, Halal

Description: Next-Gen Retinoid Delivery

Pharma-grade vitamin A powder features triple stabilization technology:

• Liposome encapsulation: 85% active retention at 40°C/6M

• UV-protective coating: Blocks 98% UVB degradation

• pH-triggered release: Activated at skin surface pH 5.5

Clinically proven to deliver 3x greater epidermal retinoid activity vs traditional retinol with 72% less irritation.

Scientific Benefits

① Precision Wrinkle Remodeling

• Stimulates type I collagen (+187% vs control)

• Reduces MMP-1 expression by 53%

• Improves epidermal thickness 29%

② Acne Pathway Control

• Inhibits 5α-reductase (IC50=8μM)

• Normalizes keratinocyte differentiation

• Reduces comedones by 61% (12-week study)

③ Photoaging Reversal

• Repairs UV-induced thymine dimers

• Increases catalase activity 2.4x

• Restores Langerhans cell density

④ Barrier Intelligence

• Boosts ceramide NS by 38%

• Enhances NMF production (+22% urea)

• Accelerates wound healing 43%

⑤ Formulation Advantages

• No pre-solubilization required

• Compatible with vitamin C/E derivatives

• Mask unpleasant retinoid odor

Application Guidelines

➀ Anti-Aging Innovations

• Night repair creams (0.1-0.5%)

• Microneedling boost serums (0.3-1%)

• Neck firming masks (0.2-0.8%)

➁ Acne Treatment Systems

• Spot treatment gels (0.5-2%)

• Sebum control toners (0.1-0.3%)

• Post-acne scar creams

➂ Body Rejuvenation

• Stretch mark creams (0.2-0.6%)

• KP (Keratosis Pilaris) treatments

• Elbow/knee brightening lotions

➃ Sun Care Synergy

• Post-sun repair emulsions

• DNA repair-enhancing SPF

• Hyperpigmentation correctors

➄ Supplement Applications

• Nutricosmetic capsules

• Gut-skin axis formulations

• Collagen synthesis boosters

Technical Specifications

• Recommended Usage:

  • Facial care: 0.05-1%

  • Body care: 0.1-2%

  • Supplements: 2500-5000 IU/g

• Synergistic Partners:

  • + Niacinamide: Irritation control

  • + Bakuchiol: Retinoid alternative

  • + Peptides: Collagen synergy

• Avoid Combinations:

  • High pH (>7.5) systems

  • Benzoyl peroxide

Clinical Validation

• 16-Week RCT (0.3% Encapsulated Retinol):

  • -39% wrinkle depth (PRIMOS®)

  • +31% skin elasticity

  • 82% reduction in irritation

  • 100% formula stability