Perillaldehyde
Perillaldehyde
Perillaldehyde
Natural Antimicrobial & Soothing Agent from Perilla for Skin Care
Basic Information
INCI Name: Perilla Ocymoides Leaf Extract (Perillaldehyde)
CAS No.: 2111-75-3
Molecular Formula: C₁₀H₁₄O
Source: Perilla frutescens leaves
Purity: 85%-98% (GC)
Appearance: Clear colorless to pale yellow liquid
Aroma: Herbaceous, mint-like
Solubility: Soluble in ethanol, oils; limited water solubility
Stability: pH 5-7, sensitive to oxidation
Description: Dual-Action Plant Powerhouse
Perillaldehyde is a monoterpenoid phenolic compound constituting 50-60% of perilla essential oil. This multifunctional ingredient combines:
Natural antimicrobial properties (effective against C. acnes)
Anti-inflammatory capabilities (COX-2 inhibition)
Antioxidant activity (ROS scavenging)
Pleasant aromatic profile for sensory enhancement
Clinically proven to control acne while calming irritated skin, making it ideal for combination skincare formulations.
Key Functional Benefits
① Acne Pathogen Control
MIC against C. acnes: 0.125% (vs. 1% salicylic acid)
Reduces comedones by 62% in 4 weeks (clinical trial)
Disrupts biofilm formation
② Inflammation Modulation
Inhibits IL-6 production by 78% at 0.5%
Suppresses histamine release
Calms post-extraction redness
③ Antioxidant Protection
Neutralizes HO• radicals (IC50: 28μM)
Protects sebum from lipid peroxidation
Enhances vitamin E stability
④ Natural Fragrance Component
Masks unpleasant actives' odors
Creates refreshing sensory profile
Aromatherapeutic stress relief
Formulation Applications
➀ Acne Treatment Systems
Prebiotic cleansing oils (0.2-0.5%)
Spot treatments (1-2%)
Clay masks with zinc PCA
➁ Sensitive Skin Care
Post-peeling recovery serums
Rosacea-friendly moisturizers
Itch-relief body lotions
➂ Natural Preservative Boost
Synergizes with levulinic acid
Reduces synthetic preservatives
pH 5.5-6.0 formulations
➃ Men's Grooming
Anti-razor burn aftershaves
Oil-control facial toners
Refreshing beard oils
➄ Aroma-Enhanced Products
Stress-relief sleep masks
Mood-boosting sheet masks
Herbal shampoo formulations